The Advantages of the Spectramax M2 Microplate Reader


Scientists in the life sciences and pharmaceutical industries strive to improve efficiency and routine laboratory processes by using products or instruments capable of processing samples in a matter of minutes or even seconds.

A microplate reader is a device used to detect chemical, biological, or physical reactions by measuring emitted light. A SpectraMax M2 microplate reader helps minimize operating time and save costs, allowing researchers to spend more time analyzing data and generating practical knowledge.

Microplate readers’ standard detection modes are absorbance, fluorescence intensity, Luminescence, time-resolved fluorescence, TR-FRET, fluorescence polarization, AlphaScreen®, and nephelometry. Depending on the type and number of detection modes, a microplate reader is classified into different categories of microplate readers.

Microplate readers by category

Multimode microplate reader

Multimode microplate readers can be equipped with up to eight detection modes. The modular configuration of these plate readers allows you to select only the detection modes that suit your current needs, with the option to add others in the future if necessary.

Absorbance microplate reader

Several microplate readers now come equipped with a UV / vis spectrometer for high-throughput, full-spectrum absorbance measurements. This allows an entire absorbance spectrum to be measured in less than 1 second per well. Some instruments can measure both microplates and cuvettes; some others offer the option to upgrade to additional detection modes at any time.

Fluorescence plate reader

Our microplate fluorimeters allow sensitive and accurate detection of any fluorescence intensity assay. Thus, it is the ideal multimode instrument for life science applications.

Luminescence microplate reader

A dedicated microplate luminometer for Flash and Glow luminescence measurements. Must be DLReady certified and upgradeable to a multimode microplate reader should your needs change.

Nephelometry Microplate Reader

A laser-based microplate nephelometer is an ideal instrument for rapid compound solubility testing in HTS and a wide range of turbidity measurements, from microbial growth to oil process control.

SpectraMax M microplate readers are based on the use of dual monochromators offering a wide range of applications. It works with 6-384 plates. The entire range features shaking and temperature control.

Detection modes include:

  • UV Visible Absorbance.
  • Fluorescence intensity (top and button).
  • Luminescence.

The spectramax m2 Multimode Microplate Reader and the spectramax m2e Multimode Microplate Reader are dual-mode, multidetector, single-chromator instruments with a triple-mode cuvette port and a plate reading capacity of 6 to 384 wells.

They are dual monochromator, multidetector instruments with a triple-mode cuvette port and 6- to 384-well plate readability.

The M2e instruments feature a triple-mode cuvette port and 6- to 384-well plate readability.

Flexibility and high sensitivity make these instruments suitable for applications in the fields of biochemistry, biochemistry, biochemistry, biochemistry, biochemistry, biochemical

fields of biochemistry, cell biology, immunology, molecular biology, and microbiology.

Typical applications include ELISA, nucleic acid, protein, enzyme assays of homogeneous type and

homogeneous and heterogeneous assays, microbial growth, endotoxin testing, and pipette calibration.

The entire SpectraMax M range includes a cuvette port for Absorbance, Fluorescence, and from SpectraMax M3 also for Luminescence.

SpectraMax readers are the only ones on the market with the versatility to evolve and adapt to every need. In addition, they allow to increase their performance sequentially from models:

M2 ‘ M2e; M3 ‘M4 ‘M5 ‘M5e.

The specific characteristics of the spectramax m2 are as follows:

  • Absorbance 200-1,000 nm: Yes
  • IF – top: Yes 
  • Dedicated cuvette port: Yes, Abs-FI 
  • IF – bottom: Yes 
  • TRF: No 
  • FP: No 
  • HTRF: No No No No No No No No Yes
  • Temperature control: Ambient +4°C to 45°C
  • Plate format: 6, 12, 24, 24, 48, 96 and 384
  • Readout mode: Endpoint, kinetic, spectral and WellScan


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